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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP7
All Species:
28.79
Human Site:
Y143
Identified Species:
45.24
UniProt:
Q93009
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93009
NP_003461.2
1102
128302
Y143
A
V
L
K
I
I
N
Y
R
D
D
E
K
S
F
Chimpanzee
Pan troglodytes
XP_510806
1102
128297
Y143
A
V
L
K
I
I
N
Y
R
D
D
E
K
S
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536979
1086
126326
D129
L
K
I
I
N
Y
R
D
D
E
K
S
F
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4J8
1103
128457
Y144
A
V
L
K
I
I
N
Y
R
D
D
D
K
S
F
Rat
Rattus norvegicus
Q4VSI4
1103
128413
Y144
A
V
L
K
I
I
N
Y
R
D
D
D
K
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506396
1145
132881
Y186
A
V
L
K
I
I
N
Y
K
D
D
E
K
S
F
Chicken
Gallus gallus
Q6U7I1
1101
128279
Y143
A
V
L
K
I
I
N
Y
K
D
D
E
K
S
F
Frog
Xenopus laevis
NP_001121282
534
61718
Zebra Danio
Brachydanio rerio
XP_691215
1103
128646
Y144
A
M
L
K
I
I
N
Y
K
D
D
E
K
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYQ8
1129
130428
H169
A
E
L
R
L
K
C
H
K
P
D
A
Q
P
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q7JKC3
1135
131579
H133
S
I
Q
K
K
I
H
H
S
F
H
N
T
E
V
Sea Urchin
Strong. purpuratus
XP_780569
1189
136707
S239
A
L
E
V
W
A
S
S
Y
S
A
M
Q
N
P
Poplar Tree
Populus trichocarpa
XP_002316470
1116
130731
K129
V
I
N
Q
L
H
Q
K
Y
S
I
R
K
D
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WU2
1115
130630
N129
A
V
V
N
Q
V
N
N
R
Y
S
I
R
K
E
Baker's Yeast
Sacchar. cerevisiae
P50101
1230
143545
H136
N
L
I
N
K
S
H
H
R
F
N
A
L
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.7
N.A.
99
99
N.A.
92.4
95.9
46
94
N.A.
48.5
N.A.
34.4
54.5
Protein Similarity:
100
99.9
N.A.
98
N.A.
99.7
99.8
N.A.
94.7
97.9
47.4
96.8
N.A.
67.5
N.A.
52.5
69.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
93.3
93.3
N.A.
93.3
93.3
0
86.6
N.A.
26.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
N.A.
20
N.A.
100
100
N.A.
100
100
0
100
N.A.
60
N.A.
40
33.3
Percent
Protein Identity:
36.9
N.A.
N.A.
36.5
29.4
N.A.
Protein Similarity:
54.3
N.A.
N.A.
54.7
47.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
0
7
0
0
0
0
7
14
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
7
47
54
14
0
14
0
% D
% Glu:
0
7
7
0
0
0
0
0
0
7
0
34
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
14
0
0
7
0
54
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
14
20
0
0
7
0
0
0
0
% H
% Ile:
0
14
14
7
47
54
0
0
0
0
7
7
0
0
0
% I
% Lys:
0
7
0
54
14
7
0
7
27
0
7
0
54
7
0
% K
% Leu:
7
14
54
0
14
0
0
0
0
0
0
0
7
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
7
14
7
0
54
7
0
0
7
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
7
% P
% Gln:
0
0
7
7
7
0
7
0
0
0
0
0
14
0
0
% Q
% Arg:
0
0
0
7
0
0
7
0
40
0
0
7
7
0
7
% R
% Ser:
7
0
0
0
0
7
7
7
7
14
7
7
0
54
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
14
% T
% Val:
7
47
7
7
0
7
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
47
14
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _